I was recently sent a news release from Alimera Sciences, who have filed an NDA requesting priority review for its Iluvien sustained release drug delivery system for treating diabetic macula edema, which if granted could result in an action letter granting approval for marketing before the end of this year. This got me thinking that I hadn’t written about ophthalmic drugs (except for Avastin and Lucentis) since I wrote about “Site Specific” Ophthalmic Drugs in June 1990, for the old Ophthalmology Management magazine. I followed that up with a series of three articles titled, On the Pharmaceutical Front – parts 1&2 appearing in the March and April 1991 issues of that same magazine, and the 3rd (and final) part began my ten-year plus run of writing a regular column (Technology Update) for Ocular Surgery News in December 1991. Back in 1990, the key words were “site specific”, i.e., drugs that were activated at the site where they were needed, under development by Xenon Vision, based o...